Molecular Biology of Cancer. Mechanisms, Targets, and Therapeutics. Lauren Pecorino. University of Greenwich. THIRD EDITION. 1. Third Edition LAUREN PECORINO Molecular Biology of Cancer This page intentionally generalcontent/cr_ pdf The Food and Drug Administration. Request PDF on ResearchGate | On Jan 1, , Lauren Pecorino and others published The Molecular Biology of Cancer: Mechanisms, Targets, and.
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Molecular Biology of Cancer: Mechanisms, Targets, and Therapeutics offers an accessible, engaging, and optimistic account of cancer biology for. Departments of Radiation Oncology/Cancer Biology Section. Molecular and Cellular Biology. Biochemistry and Molecular Biophysics. Cancer Biology Graduate. Download PDF Molecular Biology of Cancer: Mechanisms, Targets, and Book Details Author: Lauren Pecorino Pages: Binding.
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Views Total views. Actions Shares. Embeds 0 No embeds. No notes for slide. Mechanisms, Targets, and Therapeutics For Full 2. Book Details Author: Lauren Pecorino Pages: Paperback Brand: Description Molecular Biology of Cancer: Mechanisms, Targets, and Therapeutics offers an accessible, engaging, and optimistic account of cancer biology for undergraduate and graduate students. Drawing on the latest research in this dynamic field, author Lauren Pecorino makes cutting-edge science readily accessible.
Using the hallmarks of cancer as a starting point, the text looks at the cellular and molecular mechanisms underpinning the transformation of cells into cancer cells. You can change your ad preferences anytime.
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WordPress Shortcode. Published in: Full Name Comment goes here. Are you sure you want to Yes No. Be the first to like this. No Downloads. Views Total views. Actions Shares. The kinase cascades are discussed. One of the general weaknesses of many presentations is the discussion of just how do these proteins interact, at binding sites, and then whether or now one should use kinetic models applicable more appropriately to higher concentrations.
Perhaps that goes into more depth than would be necessary but I find it useful for students who have the chemistry background to grasp the concepts.
The diagrams are useful and provide constructural understanding. Chapter 5 discusses the cell cycle. The CDKs are the heart of much of this portion of mitotic growth and the author covers them in adequate detail.
Chapter 6 discusses growth inhibition and tumor suppressor genes. The heart of this is the discussion of p53 the classic control gene.
I would have liked a more detailed discussion of ubiquitin and also of the MDM proteins but again for the level of the text's audience the introduction is more than adequate. Chapter 9 on metastasis is simply stated and gives the reader a somewhat detailed overview. My only critique is that it would have been useful to have a bit more detailed discussion of the ECM, extracellular membrane, its structure, elements, and functions, with a separate subsection.
The author does refer to it and provides a reasonable first step. The author blends therapeutics very well across the presentations showing how progress is made. I would have like some discussion of pathway dynamics. There are many books which detail these approaches but perhaps again this is a bit too much. One final nit is that the experimental basis of the results would be useful to have been added, for example by an Appendix.
Overall the book is a superb addition to anyone's library on molecular cancer genomics. This is the book to review if you are behind on understanding the intricate world of cancer diagnosis, treatment, and some of the causes and origins of cancer.
Recently released this book overviews the entire gamut of identification, treatment, response, and follow up.
Perfect for medically-oriented patients, family members, or medical school students. This is NOT a book for the lay public - you need to understand medical terminology and the basics of oncology to fully appreciate. That being said, if you are bent on learning more about this area of medicine, start here! See all 29 reviews. Customers who bought this item also bought. Pages with related products.
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